What is TMG?

TMG (Betaine Anhydrous Trimethylglycine) is a food that can be found naturally in the body and also in foods such as spinach, seafood, wine, beets etc. TMG supplements are commonly used for reducing blood homocysteine levels and to improve athletic performance.

Another important function of TMG is it’s ability to help the body with methylation, which involves the transfer of a methyl group (1 carbon and 3 hydrogens) from one molecule to another in our bodies, a core component of human biochemistry. In addition methylation also enables the body to remove toxic substances in the liver and tissue. Metabolising NAD+ causes a depletion of methyl groups and taking NMN or any NAD+ enhancing supplement will potentially cause a reduction in methlylation. For this reason we recommend taking a supplement to support methylation.

Studies have shown that nicotinamide derivative supplementation can lead to an increase of metabolites in urine and blood^[3], which isn’t necessarily a bad thing but supporting the body’s ability to remove these substances from the body is important.

Our TMG supplement contains three methyl groups that are donated to the body’s natural methylation processes.

Max Lifespan recommend TMG be used alongside NMN to ensure that any nicotinamide that is not converted to NAD+ get’s methylated out of the body. An alternative is to use Methyl B12 & Methyl Folate supplementation.

Storage Information

Store in a cool dry place.

Ingredients

Pharmaceutical grade 99.8% pure TMG (Betaine Anhydrous Trimethylglycine)

Suggested Use

Add the powder to a shake or mix with a yogurt.

Side Effects

Side effects are dose related however they are not common at 500mg. They may include diarrhea, bloating, cramps, dyspepsia, nausea and vomiting.^[4]

Caution

Do not exceed recommended daily dose. Keep out of the reach of children.

Food supplements should not be used as a substitute for a varied diet.

References

^[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719041/

^[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976740/

^[3] https://www.nature.com/articles/s41598-019-46120-z

^[4] https://www.ncbi.nlm.nih.gov/books/NBK548774/

These statements have not been evaluated by the Medicines and Healthcare products Regulatory Agency. This product is not intended to diagnose, treat, cure, or prevent any disease.

The post TMG Supplement Powder appeared first on Max Lifespan.

• 99% purity
• Pharmaceutical grade
• Vegetarian & Vegan friendly
• Gluten free
• 100% GMO free
• Micronized to 600mesh for better absorption^[1]
• Potential to promote healthy aging^[2]

What is Resveratrol?

Resveratrol is a type polyphenol which are a classification of compounds that have antioxidant properties that can help protect the body against damage. It is also part of the classification of compounds known as STACs (sirtuin-activating compounds) which bind to sirtuins and altering their natural affinity for NAD+ which increases the activity of the sirtuins.

Resveratrol can be found in nature in the skin of red grapes, Japanese knotweed, berries, tea and peanuts among others.

How does Resveratrol Help with the Aging Process?

Sirtuins are genes present in humans and other organisms that protect them from disease and deterioration that occurs as part of the aging process.^[3]

Together with NMN, resveratrol supplementation can provide molecules to the body that mimic the effects sirtuins have on the genes.

As Harvard University geneticist David Sinclair Ph.D. put it ^[4]: ““You can think of resveratrol as the accelerator pedal for the sirtuin genes, and NMN as the fuel”.

Absorption

A number of resveratrol supplements on the market are sold in capsule form with large molecular size and questionable quality. These types of supplements do not absorb well and have low benefit.

Max Lifespan’s Micronized Trans-Resveratrol comes in pharmaceutical-grade powder form with 99% purity. Trans-Resveratrol is the active constituent in resveratrol and our product is micronized to 600mesh (a measure of the size of the particles). When resveratrol is micronized to this level absorption is dramatically increased which in turn creates a far greater benefit.^[5]

Storage Information

Store in cool and dry places. Keep away from strong light and heat.

Ingredients

Pharmaceutical grade 99.% pure Micronized Trans-Resveratrol.

Suggested Use

For maximum absorption mix with a natural yogurt and consume.

Side Effects

Studies have indicated that resveratrol causes no harmful side effects^[6].

Caution

Do not exceed recommended daily dose. Keep out of the reach of children.

Food supplements should not be used as a substitute for a varied diet

References

^[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173869/

^[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970218/

^[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514220/

^[4] https://www.youtube.com/watch?v=HOTS0HS7aq4

^[5] https://www.ncbi.nlm.nih.gov/pubmed/21680702

^[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164842/

These statements have not been evaluated by the Medicines and Healthcare products Regulatory Agency. This product is not intended to diagnose, treat, cure, or prevent any disease.

The post Micronized Trans-Resveratrol Supplement Powder appeared first on Max Lifespan.

• 99.7% purity
• Pharmaceutical grade
• 100% GMO free
• Stored at -20°C for stability
• Potential boost to NAD+ levels^[1]
• Potentially activates enzymes that may promote healthy aging^[2]
• Potential benefit to brain function (nootropic effect)^[3]

What is NMN?

NMN, also known as Nicotinamide Mononucleotide, is a a vitamin B3 derivative that has been shown in scientific studies to boost NAD+ levels.

NAD+ is an essential part of the biological processes in the human body and has been shown to be a factor in the aging process in animals and humans. NAD+ has been shown to be linked to the proper functioning of DNA repair, metabolism, gene expression and cell signalling in the human body.

As we get older NAD+ levels deplete and emerging evidence is suggesting that raising the levels of NAD+ may slow or even reverse some aspects of aging and furthermore halt the progress of age-related diseases.

NMN is on the very cutting edge of current anti-aging research, clinical studies in mice and yeast^[4] have shown that NMN has a positive affect on both maximum lifespan and quality of lifespan.

Human studies are underway, however given the time it takes to conduct these types of studies it may be some time before concrete results are available.

Storage Information

To ensure the maximum quality and lifespan of this product store in the freezer at approximately -20°. If this is not possible store in a fridge for a maximum of 3 months. This product will only remain stable at room temperature for approximately 2 weeks.

Ingredients

Pharmaceutical grade 99.7% pure NMN (Nicotinamide Mononucleotide)

Suggested Use

For maximum absorption first drink some water then place 1 small scoop (1g) under the tongue and hold for 2 minutes. Alternatively mix with a natural yogurt and consume.

Side Effects

Studies have indicated that NMN causes no harmful side effects^[5].

Caution

Do not exceed recommended daily dose. Keep out of the reach of children.

Food supplements should not be used as a substitute for a varied diet

References

^[1] https://www.nature.com/articles/s42255-018-0009-4, https://www.ncbi.nlm.nih.gov/pubmed/29744033, https://www.ncbi.nlm.nih.gov/pubmed/22848760

^[2] https://www.sciencedirect.com/science/article/pii/S2468501118300063, https://www.ncbi.nlm.nih.gov/pubmed/20078221, https://www.ncbi.nlm.nih.gov/pubmed/21879449, https://www.ncbi.nlm.nih.gov/pubmed/26118927

^[3] https://www.ncbi.nlm.nih.gov/pubmed/29874584

^[4] https://hms.harvard.edu/news/rewinding-clock

^[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359187/

These statements have not been evaluated by the Medicines and Healthcare products Regulatory Agency. This product is not intended to diagnose, treat, cure, or prevent any disease.

The post NMN Supplement Powder appeared first on Max Lifespan.